•Drug Use
–Taking a psychoactive substance for non-medical purposes, out of curiosity
•Drug Abuse
–Drug use that leads to problems (e.g. loss of effectiveness in society; behavioral psychopathology, criminal acts)
•Drug Dependence
–A maladaptive pattern of drug use leading to clinically-significant impairment or distress, associated with difficulty in controlling drug-taking behavior, withdrawal, and tolerance
The state of needing a drug to function within ‘normal limits’